Protease
Protease is a cosmetic ingredient used as a skin conditioning agent. It is used in 96 products in our dataset. It is regulated in the EU (listed in a Cosmetics Regulation annex). PubMed carries 24,799 studies of its skin or topical use.
| INCI name | PROTEASE |
| Function | SKIN CONDITIONING |
| CAS number | 9001-92-7 |
| EC number | 232-642-4 |
| Prevalence | 96 products (0.1% of dataset) |
| Most used in | Skincare |
| EU status | Restricted (annex ) |
| Scientific studies | 24,799 on PubMed (skin/cosmetic/topical) |
| Monthly searches | 12,100 |
Used in
Exfoliators 28.1%Face Cleansers 21.9%Makeup Removers 10.4%Toners 10.4%Lip Moisturizers 8.3%Wash Off Masks 7.3%
Frequently asked
- What does Protease do in skincare?
- Protease functions as a skin conditioning agent in cosmetic formulas.
- Is Protease allowed in cosmetics?
- Yes, but it is regulated in the EU — it appears in a Cosmetics Regulation annex with usage conditions.
- What products contain Protease?
- It is most commonly found in Skincare products, especially exfoliators (28.1% of its uses).
Manufacturers with experience using Protease
Match with vetted US contract manufacturers that have hands-on experience formulating with this ingredient.