Proline

Proline is a cosmetic ingredient used as a hair conditioning, skin conditioning agent. It is used in 417 products in our dataset. It is regulated in the EU (listed in a Cosmetics Regulation annex). PubMed carries 3,428 studies of its skin or topical use.

INCI namePROLINE
FunctionHAIR CONDITIONING, SKIN CONDITIONING
CAS number147-85-3 (L-) / 609-36-9 (dl-alpha)
EC number205-702-2 / 210-189-3
Prevalence417 products (0.45% of dataset)
Most used inSkincare
EU statusRestricted (annex )
Scientific studies3,428 on PubMed (skin/cosmetic/topical)
Monthly searches18,100

Used in

Serums 21.8%Toners 10.3%General Moisturizers 9.4%Face Cleansers 7.2%Shampoos 7%Conditioners 4.6%

Frequently asked

What does Proline do in skincare?
Proline functions as a hair conditioning, skin conditioning agent in cosmetic formulas.
Is Proline allowed in cosmetics?
Yes, but it is regulated in the EU — it appears in a Cosmetics Regulation annex with usage conditions.
What products contain Proline?
It is most commonly found in Skincare products, especially serums (21.8% of its uses).

Manufacturers with experience using Proline

Match with vetted US contract manufacturers that have hands-on experience formulating with this ingredient.