Hydroxyproline

Hydroxyproline is a cosmetic ingredient used as an antistatic, hair conditioning agent. It is used in 62 products in our dataset. It is regulated in the EU (listed in a Cosmetics Regulation annex). PubMed carries 2,298 studies of its skin or topical use.

INCI nameHYDROXYPROLINE
FunctionANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING
CAS number51-35-4
EC number200-091-9
Prevalence62 products (0.07% of dataset)
Most used inSkincare
EU statusRestricted (annex )
Scientific studies2,298 on PubMed (skin/cosmetic/topical)
Monthly searches1,600

Used in

Serums 30.6%Eye Moisturizers 8.1%Toners 8.1%General Moisturizers 6.5%Shampoos 6.5%Day Moisturizers 4.8%

Frequently asked

What does Hydroxyproline do in skincare?
Hydroxyproline functions as an antistatic, hair conditioning agent in cosmetic formulas.
Is Hydroxyproline allowed in cosmetics?
Yes, but it is regulated in the EU — it appears in a Cosmetics Regulation annex with usage conditions.
What products contain Hydroxyproline?
It is most commonly found in Skincare products, especially serums (30.6% of its uses).

Manufacturers with experience using Hydroxyproline

Match with vetted US contract manufacturers that have hands-on experience formulating with this ingredient.